Senior Expert Data Scientist - Translational Medicine

Major Accountabilities

• Conceive, design, and execute exploratory analyses as Lead Data Scientist across First in Human, Phase I-III clinical trials, applying advanced analytical methods as required. 

• Participate in and lead cross-functional biomarker collaborations with Discovery and Development partners to support target selection, clinical development, and registration activities.  

• Provide subject matter expertise for high-dimensional clinical data (genetics, omics, digital, and/or imaging) and analysis solutions to inform disease characterization, patient stratification and enrichment strategies. 

• Contribute to shaping the Novartis’ data and digital strategy by adhering to rigorous data engineering principles to unlock AI-powered discoveries. 

• Work expeditiously as a member of matrixed clinical trial teams with diverse membership and expertise. 
   

Minimum requirements 

• PhD, MD or equivalent experience in computational biology, bioinformatics, statistical genetics, biostatistics, applied machine learning or AI, data science or related field. 

• 3 years' experience in analyzing large-scale biological datasets in a drug discovery/development or relevant academic setting. 

• Expert knowledge of statistical programming in R and Bioconductor. Proficiency with Unix/Bash, Python, or similar scripting language a must. 

• Strong grasp of human genomics and next generation sequencing technologies, including experience implementing reproducible and scalable pipeline workflows in an HPC or Cloud environment. 

• Previous experience in single-cell and/or spatial transcriptomics data analyses, including TCR/BCR repertoire analysis at bulk and/or single-cell level. 

• Strong understanding of biostatistics and machine learning, including longitudinal analysis. 

• Experience with generative coding assistants, copilots and developer tools highly desirable. 

• Excellent communication and ability to translate analytical concepts for diverse audiences and stakeholders.